Before starting a thiazide diuretic for a patient with hypertension, which baseline data is crucial to obtain?

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Obtaining baseline electrolyte levels is crucial before initiating a thiazide diuretic in a patient with hypertension, as these medications can significantly affect the body’s electrolyte balance—particularly sodium and potassium. Thiazide diuretics are known for causing hyponatremia (low sodium levels) and hypokalemia (low potassium levels). By assessing the patient's electrolyte levels prior to starting the medication, the healthcare provider can identify any pre-existing imbalances and monitor for potential electrolyte disturbances after treatment initiation. This proactive approach helps inform appropriate management strategies to mitigate adverse effects.

While other assessments such as a chest X-ray, urinalysis, and EKG may provide valuable clinical information, they are not specifically essential for determining the safety and effectiveness of starting a thiazide diuretic. The emphasis here is particularly on electrolyte balance due to the pharmacological effects of thiazides, which is why monitoring electrolytes is prioritized in clinical practice.

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